The regulatory landscape across the globe is evolving at a fast rate, with more sophisticated requirements being placed on registrants and scientists. In parallel, scientific advances mean that methodologies once seen as cutting edge are becoming outdated and inadequate at addressing the new regulatory challenges.
At Envigo, our Residue Analytical Services team has been considering how to future-proof studies to better support customers through the changing pre- and post-registration regulatory and scientific environments. So how are we doing this?
Innovation through insight
We leverage our insight into the trends in the crop protection market to drive innovation in residue analysis. We use our expertise in running a wide range of studies and tackling more complex problems, to think creatively about how to overcome anticipated challenges. This helps us, and our customers, keep one step ahead. In fact, our scientists regularly present their work at industry conferences, such as the European Pesticide Residue Workshop, with some of this work receiving recognition and awards.
Another benefit of this way of thinking, combined with our state-of-the-art equipment, is the modernization of basic techniques, which leads to a rapid throughput of samples and a scaling down of reagent usage. Our annual sample throughput is over 20,000 and we can complete most development projects in less than five working days.
Think through the whole regulatory cycle
We think beyond registration. We consider how what we do pre-registration can be used post-registration to support downstream monitoring. At its simplest, this may involve validating a customer’s downstream monitoring approach. Alternatively, we may need to build the pre-registration analytics study in such a way that it can be simplified for monitoring at a later stage. Collaborative discussion and planning with clients is key to making this successful.
|QuEChERS (Quick Easy Cheap Effective Rugged Safe) methodology
is especially valuable given the drive for post-registration multi-residue
analysis of pesticides
An example of our work in this area is our use of QuEChERS (Quick Easy Cheap Effective Rugged Safe) methodology. This approach is especially valuable given the drive for post-registration multi-residue analysis of pesticides, and current developments suggest that this approach will become more common in pre-registration work.
Take an integrated approach
One of the strengths of our integrated team approach is that we can provide a seamless service between the lab and the field. We have an experienced team of Study Managers who can lead studies across both operational areas. This helps simplify the whole study approach from design, through field and lab analysis to the final study write up. In addition, quality assurance is maintained across the study, delivering reliable, consistent results in a timely fashion.
Validate, validate, validate
One of our core capabilities is in validation methodology. Internationally recognized for our work in method development and validation, in the last three years, we have run over 100 validation studies in our UK facility alone. Our colleagues in Spain support these studies by offering independent laboratory validation (ILV) where required. We have extensive experience in adapting methods to make use of more up-to-date instrument technologies, as well as utilizing current trends in extraction and clean-up techniques. This ensures that resulting methods are robust and meet the current and future expectations for the registration process.
About the Envigo Residue Analytics team
The Residue Analytics team at Envigo comprises 20 dedicated and experienced staff. We gave up counting the years of combined experience when we hit 100 years after just four people! This accumulated experience is one of the key strengths of the group and allows us to provide insightful guidance and a comprehensive and pragmatic service to our customers. Our two European residue analytics teams are in the UK and Spain; with the Barcelona office focusing on independent method validation.
Areas of expertise include the routine analysis of crops, processed commodities and soil, as well as providing analytical support for environmental fate, ecotoxicology, livestock feeding and operator exposure studies.
Here is some more information about Envigo Residue Analysis Services.
About the author
Steve Brewin has over 25 years experience as a residue chemist and joined Envigo in 1997. He steers the scientific capabilities of Residue Analytical Services including method development and mass spectroscopy services. Steve has been involved in the design of the study management plans, method validation and residue analysis activities for all study types in the Envigo portfolio.
Areas of expertise include the routine analysis of crops, processed commodities and soil, as well as providing analytical support for environmental fate, ecotoxicology, livestock feeding and operator exposure studies
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