custom antibody production blog posts

23 November, 2017

Antibody reproducibility: the importance to your research

By Richard Harrison

The production of antibodies for use in research and development and in medicine has a long history. Although there is no doubt that the use of antibodies has made a significant contribution to our basic understanding of biology, they have also been singled out as a major factor in the poor reproducibility of many biology-based studies.

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22 August, 2017

5 easy ways to avoid antibody production mistakes

By Richard Drucker

Creating highly productive cell lines requires a great level of care that starts with cell line development. Envigo’s Rook Khajenouri and Richard Drucker understand the challenges customers face throughout the process. They recently discussed some common production problems and offered solutions for ensuring consistent and reliable results that enhanced antibody production.

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13 July, 2017

5 Tips to successful monoclonal antibody production

By Richard Harrison

Monoclonal antibodies play a critical role in research, diagnostics and product development and provide numerous benefits to patients in diverse therapeutic areas.

mAbs are capable of recognizing only one epitope found on an antigen. Therefore they have greater specificity than polyclonal antibodies (pAbs), which makes them ideal for diagnostic and therapeutic uses. Custom monoclonal antibody production requires a different skillset than polyclonal antibody production, and often results in additional costs and time.

The specificity of mAbs has made them ideal for medical applications such as diagnostic and therapeutic use. So what are the key considerations in the production of monoclonal antibodies?

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23 June, 2017

6 simple secrets for polyclonal antibody production

By Richard Harrison

Careful planning and preparation is essential to produce exceptional polyclonal antibodies (pABs). Polyclonal antibodies are produced from a mixture of B lymphocytes with different epitope affinities toward the same antigen. From start to finish, pAb development takes two to six months, though custom schedules may take more time.
The first step is to select the immunizing antigen. pAbs are not suitable for some applications and monoclonal antibodies (mAbs) may be more appropriate, as discussed in the next blog article.

The first step is to select the immunizing antigen. pAbs are not suitable for some applications and monoclonal antibodies (mAbs) may be more appropriate, as discussed in the next blog article.

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19 April, 2017

6 secrets to support antibody optimization

By Richard Harrison

Carefully considering your antigen ahead of time increases the chances of yielding a high-quality antibody which will produce reliable data, ultimately saving valuable time and money.

Optimized polyclonal and monoclonal antibodies are well established, versatile reagent tools which allow for study of a wide variety of biological functions and quantification of a host of analytes. Here is Envigo’s top six secrets researchers should take into account when selecting and preparing an antigen prior to antibody generation to effectively advance research, diagnostics and therapeutic products.

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