Drug induced liver injury (DILI) is a major cause of safety-related drug withdrawal and black box warnings post-market. It is also a major cause of drug attrition during development. One of the main concerns about DILI is that it is often undetected until clinical development and/or post-market approval, when the molecule is exposed to larger populations.
So what do you need to know about DILI that will help you to reduce the risk of hepatotoxicity in humans? Here are six facts to keep in mind.
+ Read more