Oncology blog posts

20 August, 2018

5 reasons why the R2G2® mouse could help you achieve your oncology research milestones

By Jamie Naden

The R2G2® mouse has the potential to help you break new ground in investigational cancer therapies. In two recent studies, this model tolerated standard of care chemotherapy and estrogen supplementation well in terms of overall survival and changes in body weight. Here are five reasons why this mouse model could serve as an excellent host for your preclinical human tumor xenograft studies.

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22 November, 2017

Bridging studies - Why do researchers switch rodent strains?

By Travis Rothrock

Selecting the right model and rodent strain for your oncology studies can maximize the chances of success. However, there is an ever-increasing portfolio of available models and strains that may perform better than existing ones and may be more optimal for specific study purposes.

Increasing investigators are seeking to bridge from an existing rodent strain to another for their oncology preclinical efficacy and pharmacology studies. The short-term barriers associated with switching strains can appear complex and daunting, but another strain may actually be the key to the success of your oncology preclinical program.

Be sure to understand how you can benefit from switching to a new oncology rodent strain.

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19 April, 2017

How to select the right oncology model

By Travis Rothrock

Key considerations for selecting the most appropriate oncology model
Today’s breakthrough oncology treatments are the result of years of research and testing. Animal models represent an essential part of this ongoing effort to improve human health and better understand a treatment’s potential in humans. That’s why the specific model selected for testing can mean the difference between success and failure in a study.

Here we discuss the factors to consider when selecting the right animal model for your oncology research

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