Sprague Dawley blog posts

20 April, 2017

Sprague Dawley®: The workhorse of reproductive endocrinology research - part 2

By Travis Rothrock

Providing reliable learnings in reproductive endocrinology studies
An adverse fetal environment can lead to disorders and complications in an offspring’s health. From exposure to toxins to poor maternal nutrition, researchers have observed many connections that affect the reproductive potential of offspring. Sprague Dawley® SD® rats serve an important role in reproductive endocrinology studies by providing a reliable means to understand the underlying mechanisms of some of these relationships.

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20 April, 2017

Sprague Dawley®: The workhorse of reproductive endocrinology research - part 1

By Travis Rothrock

The history of advancing basic research
Infertility has profound psychological and social effects on millions of people. Despite considerable research, there remain many unanswered questions as to the potential causes of infertility or impaired fecundity. What if the humble rat could help unlock the puzzle of infertility? The Sprague Dawley® rat is no ordinary model. These rats have proven to be extremely helpful in reproductive endocrinology research.

The first Sprague Dawley® rat colony began in 1925, when Robert Dawley developed a vigorous rat with a good temperament and high rates of lactation. These rats were eventually used to study contraceptives. In 1980, the original colony was acquired by Harlan (now Envigo). These albino rats are now used widely in medical and psychological research.

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