Travis Rothrock blog posts

22 November, 2017

Best practices for bridging studies to generate data and validate a new strain

By Travis Rothrock

In this final blog on bridging studies, we provide general best-practices relevant to oncology bridging studies, including basic study design considerations and insights that are the culmination of many years of hands-on experience by Envigo experts.

+ Read more
 

22 November, 2017

The importance of bridging studies when switching strains

By Travis Rothrock

Bridging studies play an important role in drug development, both in the clinical and preclinical stages. These studies provide important information that can circumvent the repetition of entire programs. Understanding the considerations and steps in switching rodent strains and the importance of bridging studies, is critical. In this post we outline the best practices on bridging studies.

+ Read more
 

22 November, 2017

Bridging studies - Why do researchers switch rodent strains?

By Travis Rothrock

Selecting the right model and rodent strain for your oncology studies can maximize the chances of success. However, there is an ever-increasing portfolio of available models and strains that may perform better than existing ones and may be more optimal for specific study purposes.

Increasing investigators are seeking to bridge from an existing rodent strain to another for their oncology preclinical efficacy and pharmacology studies. The short-term barriers associated with switching strains can appear complex and daunting, but another strain may actually be the key to the success of your oncology preclinical program.

Be sure to understand how you can benefit from switching to a new oncology rodent strain.

+ Read more